Widening your drug discovery horizon
CellSine I series
Experience true versatility for the first time
What makes it so special ?
Study the phenomenon you want
I series devices can perform broad spectrum measurements. This allows them to register a wide variety of phenomena without the need for different assays.
Adapt it to your needs
The CellSine I series devices are modular and can be configured to accommodate up to 8 docking stations. Each of them can be addressed separately, allowing you to perform 8 different experiments at once.
Follow the events as they happen
The I series device allows you track your experiment in real time. This way you can immediately see events when they take place, avoiding unnecessary waiting.
Display data the way you want it
To extract the information you need, the I series devices come with easy to use graphing tools. They allow you to find the information that is important to you and visualize or extract it
Study your system without affecting it
Since I series devices only use weak electrical signals to gather information, the studied biological system remains unaffected. This allows for simpler experiments and more accurate results.
Protein - Protein Interaction
T Lymphocyte Activation
And Much More
How is impedance measured?
Electrical impedance is measured by applying a small alternating voltage signals to the system. By recording the resulting current the impedance can, much like is the case for resistance in Ohm's law, be calculated by dividing the potential by the current. By doing this for different voltage frequencies, the impedance spectrum can be recorded.
What does Impedance represent?
The impedance spectrum represents the electrical behavior of the studied system. Every component that is part of this system will contribute to this behavior. The studied system can be virtually anything that "fits" in a standard 96 well microtiter plate, including mammalian cells, yeasts and proteins.
How does it register biological behavior?
Depending on the biological behavior that takes place in the studied system, different changes will occur in its electrical behavior. This results in changes in the impedance spectrum. Since different types of biological behavior will cause different changes in the electrical behavior, they will alter the impedance spectrum differently. This makes it possible to easily detect and identify a variety of different activities.
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