CellSine provides unique services for high throughput screenings on the Angiotensin Converting Enzyme 2 (ACE2) and on the Angiotensin 2 Receptor (AGTR2). Both are closely related with COVID-19.
The Angiotensin-Renin-Aldosterase system plays an important role in the outcome of COVID-19. Angiotensin Converting Enzyme 2 (ACE2) is the entry place for the virus, mainly in lung epithelial cells. Because this axis plays such an important role in the regulation of blood pressure, caution is needed when considering to interfere with ACE2.
However, ACE2 offers tremendous possibilities as a target for the development of a CORONA antiviral drug.
CellSine has developed assays for all types of transmembrane receptors. We now offer services in the field of high throughput screening for the search of compounds that interfere with ACE2 in a safe way.
Want to learn more? Please do not hesitate to contact us!