Flanders health Pitch and Match
Rapid testing for infectious diseases
Numerous rapid tests for infectious disease have been developed to improve patient care. Once an infectious agent is identified, the race against the clock starts to select an appropriate treatment and unravel its mode of entry. However, many of the classic tests are endpoint assays not compatible with orthogonal assays. This has an economic impact but also lengthens the time to obtain a deep and potentially life-saving understanding of the infectious agent.
Conducting impedance measurements by the CellSine i-series overcomes most of the aforementioned limitations. Impedance-based technology offers advantages due to its purely electric nature. Compared to other methods that seek to provide MOA information, impedance measurements offer the advantage of capturing an overall cellular response in a real-time and label-free manner. The resulting impedance fingerprint may contain information about various aspects of cellular behaviour, ranging from short- or long-term cellular damage to preliminary insight into the mode of entry of the infectious agent. In addition, the same technology can be used to screen for antibiotic or antibiofilm agents in high-throughput (8*96 wells).
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